Gene therapy can transform life for people with hemophilia. But some patients don’t want it.

Bobby Wiseman, 51, was diagnosed as an infant with hemophilia, the rare genetic disease that prevents blood from clotting. He tested positive for HIV and hepatitis C when he was 11 after catching the viruses from contaminated blood-clotting products. As a teenager, he spent 45 days hospitalized in a coma from massive gastrointestinal bleeding. In 2018, he became the first patient in a study to receive an experimental gene therapy for his form of the bleeding disorder.

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